There is a fundamental flaw in the manner in which strength and defense are handled in the game. The best way to illustrate is thus:

Player A: Strength 100; Defense 20
Player B: Strength 50; Defense 50

If Player A attacks Player B, one would expect Player A to have the advantage being the attacker with more strength. Player B is in Defense mode, being attacked.
If Player B attacks Player A, one would expect Player B to have an advantage because Player A, being on the defensive, is weak.

In the game, Player A always performs better because the game is incorrectly scewed specifically for strength. This has been tested with a variety of defensive items available through the game, with the same result. Only Strength matters.

Please make this a number one priority because it is a flaw in the rules of attack vs. defense.